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1 Differential Analysis

1.1 CCI - Cell Cell Interaction

1.1.1 Interaction Plot (CCI)

Here, the cell-cell interaction is provided for each phenotype comparison between phenotypes

1.1.2 PCA CCI

Here a Principal Component Analysis (PCA) is done using the cell-cell interaction topological measures. Each measure contribution is placed in the coordinate system.

1.1.3 Pagerank Log Ratio

1.1.4 Fisher Test CCI

1.1.5 CCI Table

1.1.5.1 Table PCA CCI ADKPD_x_control

1.2 CGI - Gene Cell Interaction

1.2.1 PCA GCI

Here, a Principal Component Analysis (PCA) was done using the cell-gene interaction topological measures. High ranked observations \((>=2\sigma^{2})\) are labeled and each measure contribution is placed in the coordinate system.

1.2.2 Pagerank Log Ratio

1.2.3 PCA GCI Table

1.2.3.1 Table PCA CGI ADKPD_x_control_ggi

1.2.4 Most significant deregulated pathway per topological measure

Generates a heatmap of the most significant differentially active KEGG-pathways based on the top 100 deregulated genes.

1.3 Genes Sankey Plot: Gene-based cell-cell interaction